Endocrine Abstracts

Introduction: Hormonal replacement therapy (HRT) increases bone mineral density (BMD). Controversy exists regarding residual effect after withdrawal. We aimed to explore the effect of HRT and HRT withdrawal on: i) BMD and bone microarchitecture assessed by trabecular bone score (TBS); ii) fat (FMI), lean (LMI) and appendicular lean (ALMI) mass indexes.Methods: The OsteoLaus Cohort assessed 1500 women (50–80 years) for BMD, TBS, total energy expendit...

Introduction: Aging is associated with a decrease in muscle and bone mass, and a gain in fat mass. Similar changes are more pronounced in hypercortisolism. We previously demonstrated that high 8 PM salivary cortisol is independently associated with increased prevalence of radiologic vertebral fractures. We wanted to determine whether salivary cortisol circadian rhythm played also a role on body composition.Material and Methods: Cross-sectional study incl...